Mzere wa Caprisil Hexyl-Phenyl (-HP) HPLC

Phenyl column pogwiritsa ntchito ultra-pure silica gel ngati matrix, pamwamba pa silica gel ndi propyl bonding phenyl, π-π interactions ikufotokoza kusankha kogwirizana ndi magulu a alkane olunjika, imatha kupeza kusankha kwapadera kwa mankhwala a aromatic, kukhala ndi mawonekedwe abwino kwambiri komanso kukhudzidwa, ndikukulitsa kugwiritsa ntchito reverse phase chromatography.

Caprisil Phenyl imagwiritsa ntchito gawo la phenyl lolumikizidwa ndi hexyl. Unyolo wa hexyl alkyl umapereka chisankho chapadera komanso kukhazikika kwa hydrolytic poyerekeza ndi mankhwala olumikizidwa ndi propyl. Ukadaulo wolumikizana ndi kuchuluka kwa ma bonding umapatsa wopanga chromatograph magwiridwe antchito abwino, kulimba, komanso kubwezeretsanso bwino kwa lot-to-lot. Caprisil Phenyl Hexyl imapatsa wopanga chromatograph mgwirizano wabwino kwambiri wochokera ku phenyl kuti awonjezere magwiridwe antchito a chromatographic. Chromatogram yokhala ndi kulekanitsidwa kwachangu kwa chisakanizo cha Benzodiazepines ikuwonetsedwa pansipa. Chisakanizochi n'chovuta kulekanitsa pa mzere wamba wa phenyl.

Matrix yatsopano ya silica gel yolumikizidwa ku phenyl hexyl;

Phenyl yokhala ndi kuchuluka kwakukulu, yomwe imapereka magwiridwe antchito olekanitsa kwambiri,

Kusagwira ntchito bwino kwa zinthu, kuchepetsa kuyamwa kwa asidi ndi mankhwala oyambira, komanso kusunga kwamphamvu kwa zinthuzo;

Ingagwiritsidwe ntchito ngati chisankho choyamba cha phenyl column.

Mzere: Caprisil hexyl-phenyl 250×4.6mm, 5μm

Gawo loyenda: methanol/madzi (60/40)

Liwiro: 1 ml/mphindi

Chowunikira: UV 254nm

Kuchuluka kwa jakisoni: 10ul

Chitsanzo: 1.p-chlorophenol 2.2,4 xylenol 3.2,6 xylenol 4. Toluene 5. Adjacent dimethyl 6. paraxylene

Luso lathu lalikulu

Mndandanda wa Caprisil
Geli ya silica yoyera kwambiri, kuphimba kwapamwamba, komanso kusankha bwino kumaonetsetsa kuti kulekanitsa kumagwira ntchito bwino komanso kulondola kwa kusanthula. Imagwiritsidwa ntchito kwambiri m'mafakitale, chakudya, kuteteza chilengedwe, ndi madera ena kuti ikwaniritse zosowa zosiyanasiyana za kusanthula m'mafakitale osiyanasiyana.

Mndandanda wa ItolSep
Mzere wa asidi wa organic uli bwino kwambiri pakuwunika kwa isomer ya gulu la shuga komanso kusanthula kwa asidi wa organic.

Mndandanda wa CapriChiral
Yopangidwira kulekanitsa chiral, imapereka mitundu yosiyanasiyana ya tinthu tating'onoting'ono komanso magwiridwe antchito apadera olekanitsa chiral. Yabwino kwambiri pa zitsanzo zovuta monga zinthu zachilengedwe ndi mankhwala onunkhira, imakwaniritsa zofunikira pakuwunika kwa chiral.